Oligo Synthesis : CEPs

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5"-Carboxy-Modifier C10

Glen Research

Catalogue No.	Description	Pack Size	Price	Qty	Change to: €
10-1935-02	5"-Carboxy-Modifier C10	0.25g	£212.00£201.40Offer until : 31-Mar-2021Offer Code : GLEN55% off all Glen productsView Offer	Quantity	Add to Order
10-1935-90	5"-Carboxy-Modifier C10	100µmoles	£52.00£49.40Offer until : 31-Mar-2021Offer Code : GLEN55% off all Glen productsView Offer	Quantity	Add to Order

5"-Carboxy-Modifier C10

Glen Research

Structure

Catalog Number: 10-1935-xx

Description: 5"-Carboxy-Modifier C10

10-Carboxy-decyl-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite, N-hydroxysuccinimide ester
Formula: C₂₃H₄₀N₃O₆P	M.W.: 485.56	F.W.: varies, -CO2H = 250.23

Diluent: Anhydrous AcetonitrileAdd fresh diluent to product vial to recommended concentration and swirl vial occasionally over several minutes until product is completely dissolved. (Some oils may require between 5 and 10 minutes.) Use care to maintain anhydrous conditions. In case of transfer to alternate vial type, ensure recipient vial has been pre-dried. For more information, see http://www.glenres.com/Technical/TB_ABITransfer.pdf.

Coupling: No changes needed from standard method recommended by synthesizer manufacturer.

Deprotection: See The Glen Report, Volume 15, Number 1,March 2002, page 11.

Storage: Freezer storage, -10 to -30°C, dry

Stability in Solution: 2-3 days

Please Note: 5"-Carboxy-Modifier C10 is offered for sale under license from TriLink BioTechnologies, Inc. It is intended for research and development purposes only, and may not be used for commercial, clinical, diagnostic or any other use. It is covered under US Patent No. 6,320,041.

Note: NaOH is not compatible with dmf protecting groups.

The disulfide thiol modifier may be used for introducing 3’- or 5’-thiol linkages. Dithiol Phosphoramidite (DTPA) is a disulfide-containing modifier designed to functionalize synthetic DNA or RNA with multiple thiol groups and can be incorporated at any position of the oligonucleotide. Each DTPA addition leads to two thiol groups. This modifier was designed for optimal tethering of oligonucleotides to a gold surface but it can also be used for multiple reactions with maleimides and other thiol-specific derivatives. 5’-Carboxy-Modifier C10 is a unique linker designed to be added at the terminus of an oligonucleotide synthesis. It generates an activated carboxylic acid N-hydroxysuccinimide (NHS) ester suitable for immediate conjugation on the synthesis column with molecules containing a primary amine, resulting in a stable amide linkage. PC Amino-Modifier is a photocleavable C6 amino-modifier, part of our line of photocleavable (PC) modifiers.

5’-AminoOxy-Modifier 11 is based on a tetraethylene glycol linkage for improved solubility and for reducing the potential negative impact on hybridization of the oligo. The oxime formed from the reaction of alkyloxyamines with aldehydes creates a stable covalent bond. In comparison, the imine formed by the conjugation of primary amines with aldehydes is not stable to acidic or basic conditions and requires subsequent reduction with borohydride to form stable amine conjugates. 5’-Maleimide Modifier Phosphoramidite, developed at the University of Barcelona, incorporates a maleimide cycloadduct that is stable to ammonium hydroxide at room temperature. This phosphoramidite can be incorporated into DNA and RNA with both phosphate and phosphorothioate linkages. A retro–Diels-Alder reaction deprotects the maleimide immediately prior to conjugation.

If you cannot find the answer to your problem below then please contact us or telephone 01954 210 200

5"-Carboxy-Modifier C10

Glen Research

MSDS

Glen Report 15.1

Glen Report 19.1

Glen Report 23.1

If you cannot find the answer to your problem below then please contact us or telephone 01954 210 200

5"-Carboxy-Modifier C10

Glen Research

DILUTION/COUPLING DATA

The table below shows pack size data and, for solutions, dilutions and approximate couplings based on normal priming procedures.

ABI 392/394
Cat.No.	PackSize	Grams/Pack	0.1M Dil.(mL)	LV40	LV200	40nm	0.2µm	1µm	10µm
Cat.No.	PackSize	Grams/Pack	0.1M Dil.(mL)	Approximate Number of Additions
10-1935-02	0.25grams	.25grams	5.15	158.33	95	59.38	43.18	31.67	7.92
10-1935-90	100µmoles	.049grams	1	20	12	7.5	5.45	4	1
Expedite
Cat.No.	PackSize	Grams/Pack	Dilution(mL)	Molarity	50nm	0.2µm	1µm	15µm
Cat.No.	PackSize	Grams/Pack	Dilution(mL)	Approximate Number of Additions
10-1935-02	0.25grams	.25grams	7.68	.07	147.2	92	66.91	9.2
10-1935-90	100µmoles	.049grams	1.5	.07	23.6	14.75	10.73	1.48
Beckman
Cat.No.	PackSize	Grams/Pack	Dilution(mL)	Molarity	30nm	200nm	1000nm
Cat.No.	PackSize	Grams/Pack	Dilution(mL)	Approximate Number of Additions
10-1935-02	0.25grams	.25grams	7.68	.07	148.8	93	67.64
10-1935-90	100µmoles	.049grams	1.5	.07	25.2	15.75	11.45

If you cannot find the answer to your problem below then please contact us or telephone 01954 210 200

品牌介绍

多种天然提取的人类蛋白质产品；多种兔抗人类蛋白质抗血清。

Albumin, Human Plasma	16-16-011202
Alpha 1 Acid Glycoprotein, Human Plasma	16-16-010700
Alpha 1 Antichymotrypsin, Human Plasma	16-16-012400
Alpha 1 Antitrypsin, Human Plasma	16-16-011609
Alpha 2 Antiplasmin, Human Plasma	16-16-012901
Alpha 2 HS Glycoprotein, Human Plasma	16-16-081907
Alpha 2 Macroglobulin, Human Plasma	16-16-012013
Angiotensinogen, Human Plasma	16-16-011407
Antisera to Albumin, Human Plasma	01-16-011202
Antisera to Amylase, Human Pancreas	01-19-010000
Antisera to Apolipoprotein AI, Human Plasma	01-16-120101
Antisera to Apolipoprotein CII, Human Plasma	01-16-120302
Antisera to Azurocidin, Human Neutrophil	01-14-012621
Antisera to Catalase, Human Erythrocyte	01-05-030000
Antisera to Cathepsin B, Human Liver	01-12-030102
Antisera to Cathepsin D, Human Liver	01-12-030104
Antisera to Cathepsin H, Human Liver	01-12-030108
Antisera to Cathepsin L, Human Liver	01-12-030112
Antisera to Elastase, Human Neutrophil	01-14-051200
Antisera to Fibrinogen, Human Plasma	01-16-060902
Antisera to Kallikrein, Human Plasma	01-16-110112
Antisera to Myeloperoxidase, Human Neutrophil	01-14-130000
Antisera to Thrombospondin, Human Platelet	01-20-201319
Antisera to Trypsin, Human Pancreas	01-19-032000
Antithrombin III, Human Plasma	16-16-012020
Apolipoprotein AI, Human Plasma	16-16-120101
Apolipoprotein AII, Human Plasma	16-16-120102
Apolipoprotein AIV, Human Plasma	16-16-120104
Apolipoprotein B, Human Plasma	16-16-120200
Apolipoprotein CI, Human Plasma	16-16-120301
Apolipoprotein CII, Human Plasma	16-16-120302
Apolipoprotein CIII, Human Plasma	16-16-120303
Apolipoprotein E, Human Plasma	16-16-120500
Apotransferrin, Dog Plasma	16-16-A32001-dog
Apotransferrin, Human Plasma	16-16-A32001
Apotransferrin, Human Plasma, Low Endotoxin Level	16-16-A32001-LEL
Apotransferrin, Mouse Plasma	16-16-A32001-mouse
Apotransferrin, Rat Serum	16-16-A32001-rat
Azurocidin, Human Neutrophil (Cationic protein 37)	16-14-012621
Bacterial/Permeability-Increasing Protein, Human Neutrophil (BPI, CAP57)	16-14-021609
C1 Esterase Inhibitor, Human Plasma	16-16-031509
Calmodulin, Bovine Brain, High Purity	16-BR-030112-HP-bovine
Calpain-1, Human Erythrocyte	16-05-030112
Calpain-1, Porcine Erythrocytes	16-05-030112-P
Catalase, Human Erythrocyte	16-05-030000
Cathepsin B, Bovine Spleen	16-SP-030102-bovine
Cathepsin B, Human Liver	16-12-030102
Cathepsin D, Bovine Spleen	16-SP-030104-bovine
Cathepsin D, Human Liver	16-12-030104
Cathepsin G, Human Neutrophil	16-14-030107
Cathepsin H, Human Liver	16-12-030108
Cathepsin L, Human Liver	16-12-030112
Cathepsin S, Human Spleen	16-18-030118
Ceruloplasmin, Human Plasma	16-16-030518
Chylomicrons, Human Plasma	12-16-030825
Chymotrypsin, Human Pancreas	16-19-030820
Defensins, Alpha, Mixed from Human Neutrophils (HNP)	16-14-081416
Dipeptidyl Peptidase IV, Human Placenta	16-23-041606
Elastase, Human Neutrophil	16-14-051200
Eosinophil Cationic Protein, Human Eosinophils (ECP)	16-15-050316
Eosinophil Derived Neurotoxin, Human Eosinophils (EDN)	16-15-050414
Eosinophil Peroxidase, Human Eosinophils (EPO)	16-15-160518
Factor Va, Human Plasma	16-16-060601
GC-Globulin, Human Plasma, Mixed Type (维D结合蛋白)	16-16-070307
Haptoglobin, Human Plasma, Mixed Type	16-16-080116
Hemopexin, Human Plasma	16-16-080513
Immunoglobulin A, Human Plasma	16-16-090701
Immunoglobulin A1, Human Myeloma Protein	16-16-090701-1M
Immunoglobulin A2, Human Myeloma Plasma	16-16-090701-2M
Immunoglobulin D, Human Myeloma Plasma	16-16-090704-M
Immunoglobulin D, Human Plasma	16-16-090704
Immunoglobulin E, Human Myeloma Plasma	16-16-090705-M
Immunoglobulin E, Human Plasma	16-16-090705
Immunoglobulin G, Dog Plasma	16-16-090707-dog
Immunoglobulin G, Human Plasma	16-16-090707
Immunoglobulin G, Human Plasma, Fab Fragment	16-16-090707-Fab
Immunoglobulin G, Human Plasma, FC Fragment	16-16-090707-FC
Immunoglobulin G, Mouse Plasma	16-16-090707-mouse
Immunoglobulin G, Rat Serum	16-16-090707-rat
Immunoglobulin G1, Human Myeloma Plasma	16-16-090707-1M
Immunoglobulin G2, Human Myeloma Plasma	16-16-090707-2M
Immunoglobulin G3, Human Plasma	16-16-090707-3
Immunoglobulin G4, Human Myeloma Plasma	16-16-090707-4M
Immunoglobulin M, Fc5mu, Human Plasma	16-16-090713-Mfc5u
Immunoglobulin M, Human Myeloma Plasma	16-16-090713-M
Immunoglobulin M, Human Plasma	16-16-090713
Immunoglobulin M, mu Chain, Human Plasma	16-16-090713-MU
Kallikrein, Human Plasma	16-16-110112
Kininogen, HMW, Human Plasma	16-16-110914-H
Kininogen, LMW, Human Plasma	16-16-110914-L
Lactalbumin, Human Milk	13-16-011202
Lactoferrin, Human Neutrophil	16-14-120103
Lipoprotein a, [Lp(a)], Human Plasma	12-16-121601
Lipoproteins, High Density, Human Plasma	12-16-080412
Lipoproteins, High Density, Human Plasma, 适于细胞培养	12-16-080412-TC
Lipoproteins, Intermediate Density, Human Plasma	12-16-090412
Lipoproteins, Low Density, Human Plasma	12-16-120412
Lipoproteins, Low Density, Human Plasma, 适于细胞培养	12-16-120412-TC
Lipoproteins, Very Low Density, Human Plasma	12-16-221204
Lipoproteins, Very Low Density, Human Plasma, 适于细胞培养	12-16-221204-TC
Lysozyme, Human Neutrophil	16-14-122519
Myeloperoxidase, Human Neutrophil	16-14-130000
Plasmin, Human Plasma, Frozen	16-16-161213-F
Plasmin, Human Plasma, Lyophilized	16-16-161213-L
Plasminogen, Human Plasma	16-16-161200
Platelet Factor 4, Human Platelet	16-20-060306
Prealbumin, Human Plasma (Transthyretin)	16-16-161801
Proteinase 3, Human Neutrophil	16-14-161820
S-100 Protein, Bovine Brain	16-BR-190816-bovine
S-100b Protein, Bovine Brain	16-BR-190802-bovine
S-100αα Protein, Bovine Brain	16-BR-190801-bovine
Serum Amyloid A, Human Plasma	16-16-190101
Thrombospondin, Human Platelet	16-20-201319
Transferrin, Dog Plasma	16-16-032001-dog
Transferrin, Human Plasma	16-16-032001
Transferrin, Human Plasma, 组织培养级	16-16-032001-LEL
Transferrin, Mouse Plasma	16-16-032001-mouse
Transferrin, Rat Serum	16-16-032001-rat
Trypsin, Human Pancreas	16-19-032000
Vitronectin, Human Plasma	16-16-220920