Aptamers: Catalogue Aptamers

Hemoglobin is the iron-containing oxygen-transport metalloprotein in the red blood cells of vertebrates as well as the tissues of some invertebrates. Hemoglobin in the blood carries oxygen from the respiratory organs to the rest of the body where it releases the oxygen to burn nutrients to provide energy to power the functions of the organism, and collects the resultant carbon dioxide to bring it back to the respiratory organs to be dispensed from the organism.

This aptamer was selected by scientists at Base Pair Biotechnologies using proprietary methods and human plasma hemoglobin, [Sigma Cat #H7379] as a target and 20 mM Tris, 100 mM NaCl, 0.005% Tween20 in nuclease free water, pH 7.44. Let us know if you have any questions about its development or potential uses.

Target: Hemoglobin

Target Species: human

Target Type: protein

Affinity Constant (Kd): 4.3 nM

Default 3" Linker (Spacer) is 10T. Please submit a custom quote request for other options.

Aptamer informationKd 4.3nM

Datasheet

Please choose your modification and add as an extra catalogue number:ATWUNMOD - UnmodifiedATWAMINE - Amine modificationATWBIOTIN - Biotin modificationATWTHIOL - Thiol modification (extra charge)ATWFLUOR - Fluor (all) modification (extra charge)

If you cannot find the answer to your problem below then please contact us or telephone 01954 210 200

Antibody Equivalent Units (AEU). There is a large molecular weight difference in antibodies (typically 150,000 Da) and Base Pair’s aptamers (~14,000 Da). We provide our aptamers in terms of moles, where the aptamer moles in 1 AEU is equal to antibody moles in the typical 100 microgram shipment from a leading antibody vendor. Therefore our standard 2.5 AEU (25ug) or 5 AEU (50ug) delivery is 2.5 and 5 times the equivalent moles of a standard antibody delivery of 100 microgram respectively.

If you cannot find the answer to your problem below then please contact us or telephone 01954 210 200